Characterization of TDP-43 Delta NLS Mice: Behavior & Biomarker Analyses
Time: 2:00 pm
day: Day One PM
Details:
- Exploring TDP-43ΔNLS mouse model of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP)
- Demonstrating a motor phenotype and impaired muscle function in TDP- 43ΔNLS animals using EMG assessment
- Discussing neurofilament light chain and inflammatory markers with disease progression and TDP-43 pathology