De-risking Preclinical Strategies: Measuring Relevant Data to Optimize Successful Translation of ALS Therapies
Time: 1:00 pm
day: Pre-Conference Day Track A
Details:
Collecting the correct preclinical data is pivotal to maximise successful translation of ALS therapies into human trials. With recent candidates displaying preclinical promise but failing in clinical trials– how can preclinical strategies be adapted to maximise success translation?
Workshop highlights include:
• Selecting the correct disease model phenotype to undergo tailored safety and efficacy testing for selective therapeutic targets
• Target engagement and disease modification: solidifying preclinical endpoints to optimize successful translation to human trials
• Developing translatable biomarkers to validate desired therapeutic effects
