Sam Alworth

Sam Alworth

Company: AcuraStem Inc.

Job title: Chief Executive Officer


Leveraging Accurate Human Disease Models for Target Validation & Drug Optimization to Rapidly Advance Novel & Effective Treatments for ALS 11:45 am

Discovering novel and broadly effective therapeutic targets, such as PIKFYVE and SYF, through unbiased screening in sporadic ALS patient models Optimizing ASO drug candidates’ potency to reverse aberrant UNC13A splicing in ALS patient models Investigating safety, potency and biodistribution of lead ASO candidate AS-202, a near-to-clinic PIKFYVE suppressing ASORead more

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