Assessing Neurofilament Light Changes in Presymptomatic Sporadic ALS

Time: 8:00 am
day: Conference Day One Morning


  • Understanding NfL changes prior to ALS diagnosis is critical to understanding disease pathology and planning for better diagnosis and clinical trial
  • Large population datasets are critical to drive insights in presymptomatic individuals
  • Using the UK biobank we characterized changes in NfL up to 10 years prior to ALS diagnosis