Workshop D: Establishing Adaptive & Decentralized Models to Accelerate Therapeutic Discovery in ALS
Time: 1:30 pm
day: Pre Conference Workshop D Track
Details:
This workshop will explore the transformative potential of adaptive and decentralized clinical trial designs in ALS research. By integrating platform trials, multi-arm designs, and decentralized tools, these approaches aim to enhance trial efficiency, broaden patient access, and improve the trial experience for participants. Discussions will focus on optimizing recruitment, leveraging interim data for trial modifications, and utilizing digital tools to reduce patient burden while ensuring regulatory alignment.
- Evaluate adaptive trial designs, including platform trials and response-adaptive randomization, optimize recruitment, improve data collection, and enhance trial efficiency
- Explore strategies to improve patient engagement, streamline enrollment, and diversify participation while maintaining trial integrity
- Assess decentralized trial methodologies such as remote monitoring, self-reported ALS-FRS-R, and home visits to mitigate patient burden and foster inclusivity
- Examine operational challenges and regulatory requirements for implementing these models effectively in ALS research
