Wen-Hsuan Chang

Company: AcuraStem Inc.

Job title: Head of Target Validation

Seminars:

Roundtable Discussion: Reinventing the ALS Target Landscape 2:30 pm

More practical and highly interactive breakout roundtables where attendees can crowd-source solutions and share opinions around pre-assigned topic areas: Looking beyond TDP-43: Are there other RNA binding protein dysfunctions involved in sporadic ALS? Are their specific genetic mutations in ALS that could be addressed with RNA editing technologies? What are the most promising microglia and…Read more

day: Day One PM

Panel Discussion: Expanding the In Vitro Toolbox to Bring Additional Translational Value to iPSC-Derived Models 12:00 pm

Exploring additional avenues to enhance in vitro studies of ALS pathology Evaluating the ability to model neuromuscular junctions with sophisticated systems, such as organoids, microfluidics and synaptoneurosomes Debating the feasibility of employing novel in vitro methods for preclinical studies in industryRead more

day: Day One Track A AM

Employing iPSC-Derived Motor Neurones to Model Diverse Forms of ALS 11:00 am

Outlining innovative ways to recapitulate sporadic ALS with no isogenic control present Ensuring confidence in the differentiation stimulus to induce a truly sporadic ALS phenotype Enhancing the translational value of iPSC-derived models and ability to replicate sporadic ALS in the clinicRead more

day: Day One Track A AM